Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.47 |
| ▸ | HPGDS | O60760 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320654 | 0.76 | PDE10A (0.63) | PDE10AHPGDSWDR5 | |
| SCHEMBL16003606 | 0.76 | PDE10A (0.58) | PDE10AHPGDS | |
| SCHEMBL16320826 | 0.75 | — | — | |
| SCHEMBL16003607 | 0.74 | PDE10A (0.49) | PDE10AWDR5ALDH1A1KDM4E | |
| SCHEMBL28336179 | 0.73 | PDE10A (0.47) | PDE10AHPGDSWDR5KMO | |
| Hydrochloric Acid SCHEMBL16341367 | 0.73 | PDE10A (0.48) | PDE10AWDR5ALDH1A1KDM4E | |
| SCHEMBL16340755 | 0.73 | GPR119 (0.35) | HPGD | |
| SCHEMBL16320708 | 0.70 | PDE10A (0.43) | PDE10A | |
| SCHEMBL16320986 | 0.70 | PDE10A (0.42) | PDE10A | |
| SCHEMBL1921490 | 0.68 | SIGMAR1 (0.56) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | PDE10A 1/4885HPGDS 2649/4885WDR5 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.