Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.39 |
| ▸ | FPR2 | P25090 | 7/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16003886 | 0.78 | NOTUM (0.45) | PDE10ASCN9AGRM5NPC1RAB9A | |
| SCHEMBL16003900 | 0.77 | NPC1 (0.42) | PDE10ASCN9AFPR2GRM5NPC1 | |
| Hydrochloric Acid SCHEMBL16341551 | 0.76 | NPC1 (0.41) | PDE10ASCN9AFPR2GRM5NPC1 | |
| SCHEMBL16340966 | 0.76 | PDE10A (0.43) | PDE10AGRM5CLPPNPC1RAB9A | |
| SCHEMBL16320445 | 0.75 | PDE10A (0.58) | PDE10A | |
| SCHEMBL28171807 | 0.71 | HSD11B1 (0.63) | NPC1RAB9ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL16320986 | 0.70 | PDE10A (0.42) | PDE10AGRM5KMT2AMEN1 | |
| SCHEMBL28335954 | 0.69 | HPGD (0.36) | SCN9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20854927 | 0.68 | NPC1 (0.46) | PDE10ANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28336179 | 0.68 | PDE10A (0.47) | PDE10AGRM5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957317-B | Novel pyrazole derivatives | 持田制药株式会社 | 2019-12-31 | — | — | CN | disclosed |