Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.39 |
| ▸ | PSMD11 | O00231 | 4/20 | 0.39 |
| ▸ | PSMD12 | O00232 | 4/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.39 |
| ▸ | PSMD3 | O43242 | 4/20 | 0.39 |
| ▸ | PSMC3 | P17980 | 4/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.39 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.39 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.39 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328494 | 0.99 | CTSL (0.41) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL16328495 | 0.94 | SIRT6 (0.34) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL16328487 | 0.94 | SIRT6 (0.34) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL16328488 | 0.94 | SIRT6 (0.34) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL16328489 | 0.94 | SIRT6 (0.34) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL16328499 | 0.90 | PSMB5 (0.47) | PSMB11PSMD11PSMD12PSMD14PSMA7 | |
| SCHEMBL16328492 | 0.85 | PSMB11 (0.32) | PSMB11PSMD11PSMD12PSMD14PSMA7 | |
| SCHEMBL16328486 | 0.85 | TDP1 (0.35) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL13625020 | 0.84 | CTSB (0.42) | CTSLCTSBPSMB11PSMD11PSMD12 | |
| SCHEMBL13625027 | 0.84 | CTSB (0.42) | CTSLCTSBPSMB11PSMD11PSMD12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287910-B2 | Polymeric micelles for polynucleotide encapsulation | INTEZYNE TECHNOLOGIES, INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-20100278927-A1 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278927-A1 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | NCL, POLN, CHMP4B | CTSL 4350/4885CTSB 3462/4885PSMB11 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.