SCHEMBL16328752

SCHEMBL16328752

O=C(O)CCC1C(=O)C=CC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.40
NPSR1 Q6W5P4 1/20 0.38
LMNA P02545 2/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
FOLH1 Q04609 1/20 0.36
KDM4E B2RXH2 1/20 0.36
PTGS1 P23219 4/20 0.35
PTGS2 P35354 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
PPARG P37231 2/20 0.34
ABL1 P00519 1/20 0.34
IDE P14735 1/20 0.34
RIN1 Q13671 1/20 0.34
NR2E3 Q9Y5X4 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
F13A1 P00488 3/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22798363 0.83 PPARG (0.49) LMNAPTGS1PTGS2TDP1PPARG
SCHEMBL10483635 0.83 PPARG (0.49) LMNAPTGS1PTGS2TDP1PPARG
SCHEMBL22814629 0.72 PTGS1 (0.45) LMNAPTGS1PTGS2TDP1PPARG
SCHEMBL3875150 0.70 LMNA (0.41) LMNAALKBH5SUCNR1EGLN1PTGS1
SCHEMBL15236130 0.69 PPARG (0.43) NPSR1LMNAFOLH1KDM4EPTGS1
SCHEMBL21727082 0.69 PAOX (0.42) LMNATDP1PPARGABL1IDE
SCHEMBL12972924 0.69 FOLH1 (0.42) NPSR1FOLH1KDM4EPTGS1PTGS2
SCHEMBL5077782 0.68 NPSR1 (0.43) EGFRNPSR1LMNAALKBH5SUCNR1
SCHEMBL17930204 0.68 HSD17B10 (0.42) EGFRNPSR1LMNAFOLH1KDM4E
SCHEMBL15630449 0.68 PTGS1 (0.37) NPSR1LMNAALKBH5SUCNR1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed
US-20110172390-A1 Protein-Proteophore Complexes ASCENDIS PHARMA A/S (DK) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172390-A1 Protein-Proteophore Complexes PSMG3, PSME1, PSMD11 EGFR 3339/4885NPSR1 4245/4885LMNA 1629/4885
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID SNRPA, NSUN2, POLRMT EGFR 2098/4885NPSR1 1786/4885LMNA 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.