Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567092 | 0.80 | PNMT (0.43) | SLC1A3SLC1A2SLC1A1PARP10CYP1A2 | |
| SCHEMBL15751163 | 0.79 | TSHR (0.47) | CYP1A2CYP2C19CYP2C9ALDH1A1KMT2A | |
| SCHEMBL9035787 | 0.78 | CASR (0.48) | SLC1A3SLC1A2SLC1A1CYP1A2CYP2C19 | |
| SCHEMBL10819592 | 0.75 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1PARP10CYP1A2 | |
| SCHEMBL31432573 | 0.75 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1PARP10CYP1A2 | |
| SCHEMBL16247743 | 0.73 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1PARP10CYP1A2 | |
| SCHEMBL24372107 | 0.73 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2C9ALDH1A1MEN1 | |
| SCHEMBL5608955 | 0.73 | ALDH1A1 (0.50) | CYP1A2CYP2C19CYP2C9ALDH1A1MEN1 | |
| SCHEMBL14443332 | 0.72 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1PARP10CYP1A2 | |
| SCHEMBL28480565 | 0.72 | MEN1 (0.54) | SLC1A3SLC1A2SLC1A1PARP10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611805-A1 | FUSED TRIAZOLES FOR THE TREATMENT OR PROPHYLAXIS OF MILD COGNITIVE IMPAIRMENT | Takeda Pharmaceutical Company Limited (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029991-A1 | FUSED TRIAZOLES FOR THE TREATMENT OR PROPHYLAXIS OF MILD COGNITIVE IMPAIRMENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-08 | — | — | WO | disclosed |