Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037027 | 0.93 | ALDH1A1 (0.42) | NAAATSHRALDH1A1LMNA | |
| SCHEMBL10353701 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL1978843 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL9511157 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL7715586 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL130784 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL10353311 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL1978841 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL3326271 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 | |
| SCHEMBL3326274 | 0.83 | CNR1 (0.49) | NAAAPPARGEPHX1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-28 | — | — | US | disclosed |
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274173-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | NAAA 1893/4885PPARG 4760/4885EPHX1 4446/4885 |
| US-20160215093-A1 | STABLE HELICAL IONIC POLYPEPTIDES | GHITM, SLC7A1, PICALM | NAAA 1893/4885PPARG 4760/4885EPHX1 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.