Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Isobutyl Ketone SCHEMBL9328768 | 0.96 | ALDH1A1 (0.54) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| Methyl Isobutyl Ketone SCHEMBL11007468 | 0.94 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| Methyl Isobutyl Ketone SCHEMBL8727203 | 0.94 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| Methyl Isobutyl Ketone SCHEMBL10487290 | 0.94 | ACHE (0.56) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| P-Xylene SCHEMBL28115019 | 0.93 | TDP1 (0.50) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| Methyl Isobutyl Ketone SCHEMBL11127111 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| P-Xylene SCHEMBL28174939 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| O-Xylene SCHEMBL9644431 | 0.89 | ALDH1A1 (0.47) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| P-Xylene SCHEMBL27317096 | 0.89 | TDP1 (0.67) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT | |
| Methyl Isobutyl Ketone SCHEMBL17510087 | 0.88 | TDP1 (0.45) | ALDH1A1TDP1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109229-B | Anti-yellowing and temperature-resistant tetrafunctional epoxy resin and preparation method thereof | 广东诚展科技股份有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-115109229-A | Yellowing-resistant and temperature-resistant four-functional-group epoxy resin and preparation method thereof | 河源诚展科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-108794342-A | Ammonium carboxylate salt compound, its crystal form, amorphous substance and preparation method thereof | 武汉朗来科技发展有限公司 | 2018-11-13 | — | — | CN | claimed |
| US-20070060756-A1 | Process for the preparation of desloratadine | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2007-03-15 | — | — | US | claimed |
| JP-6001741-A | — | — | None | — | — | JP | disclosed |
| EP-4400498-A1 | AMORPHOUS SUBSTANCES, CRYSTALS, PHARMACEUTICAL COMPOSITIONS, PREPARATION METHODS AND USES OF THIOHYDANTOIN COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |
| CN-118235089-A | Curable resin composition, laminated structure, cured product, and electronic component | 太阳控股株式会社 | 2024-06-21 | — | — | CN | disclosed |
| US-20240190815-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | SPRINGWORKS THERAPEUTICS, INC. | 2024-06-13 | — | — | US | disclosed |
| CN-113196171-B | Curable resin composition, dry film, cured product, and electronic component | 太阳控股株式会社 | 2024-04-23 | — | — | CN | disclosed |
| CN-117850164-A | Curable resin composition, dry film, cured product, and printed wiring board | 太阳控股株式会社 | 2024-04-09 | — | — | CN | disclosed |
| US-11884610-B2 | Crystalline solids of mek inhibitor n-((r)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| CN-117120930-A | Laminated structure, dry film, cured product, and electronic component | 太阳油墨制造株式会社 | 2023-11-24 | — | — | CN | disclosed |
| US-4406771-A | Solvent dewaxing waxy hydrocarbon oil distillates using a combination poly di-alkyl fumarate-vinyl acetate copolymer having pendent carbon side chain length of predominantly C22 and polyalkyl(meth-)acrylate polymer dewaxing aid | EXXON RESEARCH AND ENGINEERING CO. (US) | 1983-09-27 | — | — | US | disclosed |
| US-4297271-A | CHROMAGEN IN A DIAGNOSTIC TEST FOR FECAL BLOOD; CHROMATOGRAPHY | BOEHRINGER MANNHEIM GMBH (DE) | 1981-10-27 | — | — | US | disclosed |
| EP-0015655-A1 | Process for coating articles by electrodeposition, compositions for use in the process and coated articles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-09-17 | — | — | EP | disclosed |
| US-4219336-A | HYDROGEN PEROXIDE, GUAIACONIC ACID | BOEHRINGER MANNHEIM GMBH (DE) | 1980-08-26 | — | — | US | disclosed |
| US-4177177-A | Polymer emulsification process | LEHIGH UNIVERSITY | 1979-12-04 | — | — | US | disclosed |
| US-4085250-A | ORGANO TITANATE LATENT CATALYST | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4068040-A | CROSSLINKED POLYMERIC BINDER | FUJI PHOTO FILM CO., LTD. (JA) | 1978-01-10 | — | — | US | disclosed |
| US-3998983-A | Resin rich epoxide-mica flexible high voltage insulation | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884610-B2 | Crystalline solids of mek inhibitor n-((r)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | NRAS, BRAF, KSR2 | ALDH1A1 3605/4885TDP1 2584/4885SMN1; SMN2 2635/4885 |
| US-20070060756-A1 | Process for the preparation of desloratadine | HRH2, HRH1, HRH4 | ALDH1A1 596/4885TDP1 3612/4885SMN1; SMN2 2824/4885 |
| US-20240190815-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | NRAS, BRAF, KSR2 | ALDH1A1 3466/4885TDP1 2271/4885SMN1; SMN2 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.