Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701560 | 0.85 | THRB (0.46) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL3697121 | 0.81 | NOTUM (0.34) | NOTUM | |
| SCHEMBL3703976 | 0.81 | NOTUM (0.33) | SLC6A9NOTUM | |
| SCHEMBL4130894 | 0.81 | SLC6A9 (0.36) | KMT2AMEN1MAPTHTTSLC6A9 | |
| SCHEMBL4130901 | 0.81 | TP53 (0.34) | KMT2AMEN1MAPTSLC6A9NOTUM | |
| SCHEMBL3805131 | 0.78 | SLC6A9 (0.36) | MAPTSLC6A9 | |
| SCHEMBL3692392 | 0.77 | TP53 (0.45) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL476490 | 0.77 | ELANE (0.40) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL3707175 | 0.76 | SLC6A9 (0.33) | MAPTHTTSLC6A9LMNAL3MBTL1 | |
| SCHEMBL3805129 | 0.74 | HTR2C (0.45) | MAPTSLC6A9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |