Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334448 | 0.92 | CA12 (0.54) | ALDH1A1LMNAPKMTSHRCYP1A2 | |
| SCHEMBL16334725 | 0.91 | BCL2A1 (0.47) | ALDH1A1LMNAKMT2ACA12CA9 | |
| SCHEMBL16335284 | 0.88 | MEN1 (0.54) | ALDH1A1LMNAPKMTSHRKMT2A | |
| SCHEMBL16335125 | 0.88 | ALPL (0.54) | ALDH1A1LMNAKMT2AMEN1ALPL | |
| SCHEMBL16335001 | 0.86 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMTSHRCYP1A2 | |
| SCHEMBL16334444 | 0.86 | P2RY12 (0.48) | ALDH1A1LMNAPKMCA12CA9 | |
| SCHEMBL16335056 | 0.86 | HTR7 (0.47) | ALDH1A1LMNACYP2C19KMT2AMEN1 | |
| SCHEMBL16334633 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAPKMTSHRCYP1A2 | |
| Bromide SCHEMBL16334938 | 0.85 | HTR7 (0.46) | ALDH1A1LMNACYP2C19KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL16334184 | 0.85 | HTR7 (0.46) | ALDH1A1LMNACYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207508-A1 | PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | WO | disclosed |