Methacrylic Acid

Methacrylic Acid

SCHEMBL16335447

C=C(C)C(=O)O.CC(C)CCOCCC(C)C

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.42
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 2/20 0.38
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
THRB P10828 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA1 P00915 3/20 0.33
PKM P14618 1/20 0.33
THRA P10827 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11138704 0.86 TDP1 (0.46) TDP1ALDH1A1HSD17B10KDM4EMAPK1
Methacrylic Acid SCHEMBL28905450 0.82 TSHR (0.57) TDP1TSHRALDH1A1HSD17B10KDM4E
SCHEMBL15759437 0.82 TDP1 (0.41) TDP1TSHRALDH1A1HSD17B10KDM4E
SCHEMBL12056558 0.80 THRB (0.61) TDP1TSHRALDH1A1HSD17B10KDM4E
Methacrylic Acid SCHEMBL3647935 0.77 TSHR (0.56) TDP1TSHRALDH1A1KDM4ETHRB
Methacrylic Acid SCHEMBL31589114 0.77 TDP1 (0.42) TDP1TSHRALDH1A1CA1BLM
SCHEMBL27953144 0.77 TDP1 (0.43) TDP1ALDH1A1HSD17B10KDM4EMAPK1
Methacrylic Acid SCHEMBL28642481 0.76 TSHR (0.37) TSHRALDH1A1MAPK1NOS3NOS1
SCHEMBL5569319 0.76 TDP1 (0.40) TDP1TSHRALDH1A1HSD17B10KDM4E
SCHEMBL11762397 0.76 TDP1 (0.42) TDP1ALDH1A1HSD17B10KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds L'OREAL (FR) 2021-09-28 US disclosed
US-9884003-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9884004-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9884002-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9814668-B2 Hair styling compositions comprising latex polymers L'OREAL (FR) 2017-11-14 US disclosed
US-9814669-B2 Hair cosmetic composition containing latex polymers and a silicone-organic polymer compound L'OREAL (FR) 2017-11-14 US disclosed
US-9795556-B2 Compositions and methods for treating hair L'OREAL (FR) 2017-10-24 US disclosed
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND L'OREAL (FR) 2016-06-23 US disclosed
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004115-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004118-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, NACA, DPM1 TDP1 365/4885TSHR 3323/4885ALDH1A1 861/4885
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND SUCLG1, NACA, EPM2A TDP1 1506/4885TSHR 2270/4885ALDH1A1 430/4885
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds SRM, KRT18, ODC1 TDP1 1363/4885TSHR 4075/4885ALDH1A1 973/4885
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, DPM1, NACA TDP1 341/4885TSHR 4108/4885ALDH1A1 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.