Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichlorobenzene SCHEMBL29182241 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1PKMTAAR1 | |
| Trolamine SCHEMBL3893278 | 0.75 | TDP1 (0.55) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4975914 | 0.75 | KMT2A (0.47) | TSHRLMNAMAPTMEN1KMT2A | |
| 1,2-Dichlorobenzene SCHEMBL4065607 | 0.74 | TSHR (0.56) | TSHRLMNAALDH1A1HTTPKM | |
| Trolamine SCHEMBL9541967 | 0.73 | TSHR (0.67) | TSHRLMNAMEN1KMT2AKDM4E | |
| 1,2-Dichlorobenzene SCHEMBL9003449 | 0.73 | TSHR (0.62) | TSHRLMNAALDH1A1PKMTAAR1 | |
| SCHEMBL6567560 | 0.71 | OPRK1 (0.60) | HTTTAAR1AOC3 | |
| Trolamine SCHEMBL21591942 | 0.71 | TSHR (0.50) | TSHRLMNAMEN1KMT2AKDM4E | |
| Trolamine SCHEMBL149116 | 0.71 | KDM4E (0.42) | TSHRLMNAMAPTMEN1KMT2A | |
| Trolamine SCHEMBL17938713 | 0.71 | MAPT (0.43) | TSHRLMNAMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228414-A1 | METHOD FOR EXTERNAL EAR CANAL PRESSURE REGULATION TO ALLEVIATE DISORDER SYMPTOMS | NOCIRA, LLC | 2021-07-29 | — | — | US | disclosed |
| US-10772766-B2 | Method for external ear canal pressure regulation to alleviate disorder symptoms | NOCIRA, LLC (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190231597-A1 | METHOD FOR EXTERNAL EAR CANAL PRESSURE REGULATION TO ALLEVIATE DISORDER SYMPTOMS | GBS VENTURES LLC | 2019-08-01 | — | — | US | disclosed |
| US-10251790-B2 | Method for external ear canal pressure regulation to alleviate disorder symptoms | NOCIRA, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-20150000678-A1 | Method For External Ear Canal Pressure Regulation To Alleviate Disorder Symptoms | GBS VENTURES LLC (US) | 2015-01-01 | — | — | US | disclosed |