Trolamine

Trolamine

SCHEMBL149116

OCCN(CCO)CCO.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
HTT P42858 2/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 4/20 0.36
ALDH1A1 P00352 4/20 0.36
TSHR P16473 4/20 0.36
HSD17B10 Q99714 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP2C19 P33261 1/20 0.36
SCN1A P35498 1/20 0.36
HIF1A Q16665 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL21410323 0.98 KDM4E (0.41) KDM4EHTTMEN1KMT2ASMN1; SMN2
Trolamine SCHEMBL22973396 0.98 KDM4E (0.41) KDM4EHTTMEN1KMT2ASMN1; SMN2
SCHEMBL29073950 0.77 HTR1A (0.46) LMNAALDH1A1TSHRHSD17B10CYP3A4
Trolamine SCHEMBL3893278 0.76 TDP1 (0.55) KDM4EHTTMEN1KMT2ASMN1; SMN2
Trolamine SCHEMBL3320439 0.74 TDP1 (0.37) LMNAALDH1A1TSHRHSD17B10TDP1
Trolamine SCHEMBL9541967 0.74 TSHR (0.67) KDM4EHTTMEN1KMT2ALMNA
SCHEMBL2576243 0.74 MEN1 (0.49) HTTMEN1KMT2ATDP1OPRM1
SCHEMBL11707018 0.74 ALDH1A1 (0.50) HTTSMN1; SMN2LMNAALDH1A1TSHR
SCHEMBL143876 0.74 ALDH1A1 (0.50) HTTSMN1; SMN2LMNAALDH1A1TSHR
Benzene SCHEMBL31091106 0.74 ALDH1A1 (0.50) HTTSMN1; SMN2LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102222-A1 DENTAL CURABLE COMPOSITION, DENTAL BLANK FOR CUTTING, METHOD OF PRODUCING A SILICA COMPOSITE OXIDE PARTICULATE, AND DENTAL FILLER TOKUYAMA DENTAL CORP (JP) 2026-04-16 US disclosed
EP-4595944-A1 DENTAL CURABLE COMPOSITION, BLANK FOR DENTAL-CUTTING WORK, PRODUCTION METHOD FOR SILICA-BASED COMPOSITE OXIDE POWDER BODY, AND DENTAL FILLER Tokuyama Dental Corporation (JP) 2025-08-06 EP disclosed
WO-2025022795-A1 METHOD FOR PRODUCING RADIOPAQUE FILLER AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION 株式会社トクヤマデンタル 2025-01-30 WO disclosed
WO-2024180894-A1 CURABLE DENTAL COMPOSITION 株式会社トクヤマデンタル 2024-09-06 WO disclosed
CN-118175982-A Mixed resin-based material for dental cutting and method for producing dental crown 株式会社德山齿科 2024-06-11 CN disclosed
WO-2024070260-A1 DENTAL CURABLE COMPOSITION, BLANK FOR DENTAL-CUTTING WORK, PRODUCTION METHOD FOR SILICA-BASED COMPOSITE OXIDE POWDER BODY, AND DENTAL FILLER 株式会社トクヤマデンタル 2024-04-04 WO disclosed
EP-2216349-B1 USE OF A PHENOL TYPE COMPOUND IN A DENTAL CHEMICAL POLYMERIZATION CATALYST WITH IMPROVED POLYMERIZING ACTIVITY TOKUYAMA DENTAL CORP (JP) 2023-09-20 EP disclosed
CN-111902119-B Resin block for dental cutting 德山齿科株式会社 2023-06-06 CN disclosed
WO-2023074456-A1 HYBRID RESIN-BASED BLANK FOR DENTAL CUTTING, AND METHOD FOR MANUFACTURING CROWN 株式会社トクヤマデンタル 2023-05-04 WO disclosed
CN-113840590-B Dental cutting material and method for manufacturing same 株式会社德山齿科 2023-04-18 CN disclosed
US-20110255272-A1 Simulated candle apparatus PRIVAS YVES 2011-10-20 US disclosed
US-20100304961-A1 DENTAL CHEMICAL POLYMERIZATION CATALYST AND DENTAL CURABLE COMPOSITION CONTAINING THE SAME CATALYST TOKUYAMA DENTAL CORPORATION (JP) 2010-12-02 US disclosed
EP-2216349-A1 CHEMICAL POLYMERIZATION CATALYST FOR DENTAL USE AND CURABLE DENTAL COMPOSITIONS CONTAINING THE CATALYST Tokuyama Dental Corporation (JP) 2010-08-11 EP disclosed
US-7683106-B2 Primer for dental materials and pulp capping agent for dentin regeneration NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) 2010-03-23 US disclosed
US-20090258966-A1 Dental Composition NIHON UNIVERSITY (JP) 2009-10-15 US disclosed
US-20060252846-A1 Primer for dental materials and pulp capping agent for dentin regeneration MITSUBISHI CHEMICAL CORPORATION (JP) 2006-11-09 US disclosed
US-7084182-B2 Photopolymerization initiator TOKUYAMA CORPORATION (JP) 2006-08-01 US disclosed
EP-1457190-B1 Photopolymerization initiator TOKUYAMA CORP (JP) 2006-06-21 EP disclosed
US-20040180983-A1 Photopolymerization initiator TOKUYAMA DENTAL CORPORATION (JP) 2004-09-16 US disclosed
EP-1457190-A1 Photopolymerization initiator Tokuyama Corporation (JP) 2004-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102222-A1 DENTAL CURABLE COMPOSITION, DENTAL BLANK FOR CUTTING, METHOD OF PRODUCING A SILICA COMPOSITE OXIDE PARTICULATE, AND DENTAL FILLER RCC1, CA1, SSRP1 KDM4E 880/4885HTT 2122/4885MEN1 2291/4885
US-20090258966-A1 Dental Composition DCPS, MMAB, CAD KDM4E 2517/4885HTT 1620/4885MEN1 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.