SCHEMBL16337485

SCHEMBL16337485

CC(=CC(C)C=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
PTGS1 P23219 1/20 0.33
AKR1C3 P42330 1/20 0.33
APEX1 P27695 3/20 0.32
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8726425 0.86 PTGS1 (0.37) FFAR3LCKFYNPTGS1AKR1C3
SCHEMBL8726421 0.86 PTGS1 (0.37) FFAR3LCKFYNPTGS1AKR1C3
Acetic Acid SCHEMBL10488048 0.81 FFAR3 (0.39) FFAR3LCKFYNPTGS1AKR1C3
SCHEMBL21714 0.78
SCHEMBL6573659 0.78
SCHEMBL21716 0.78
SCHEMBL2119773 0.77 ALDH1A1 (0.35) PTGS1AKR1C3APEX1
SCHEMBL9614929 0.77 FFAR3 (0.35) FFAR3LCKFYNPTGS1AKR1C3
SCHEMBL27718847 0.77 PTGS1 (0.32) PTGS1AKR1C3APEX1
SCHEMBL9168851 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds L'OREAL (FR) 2021-09-28 US disclosed
US-9884003-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9884004-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9884002-B2 Compositions and methods for treating hair L'OREAL (FR) 2018-02-06 US disclosed
US-9814668-B2 Hair styling compositions comprising latex polymers L'OREAL (FR) 2017-11-14 US disclosed
US-9814669-B2 Hair cosmetic composition containing latex polymers and a silicone-organic polymer compound L'OREAL (FR) 2017-11-14 US disclosed
US-9795556-B2 Compositions and methods for treating hair L'OREAL (FR) 2017-10-24 US disclosed
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND L'OREAL (FR) 2016-06-23 US disclosed
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004115-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed
US-20150004118-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150004116-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, NACA, DPM1 FFAR3 3857/4885LCK 1212/4885FYN 403/4885
US-20160175237-A1 HAIR COSMETIC COMPOSITION CONTAINING LATEX POLYMERS AND A SILICONE-ORGANIC POLYMER COMPOUND SUCLG1, NACA, EPM2A FFAR3 2407/4885LCK 1095/4885FYN 708/4885
US-11129787-B2 Cosmetic compositions containing oxazoline functionalized polymers and polyamine compounds SRM, KRT18, ODC1 FFAR3 2821/4885LCK 163/4885FYN 211/4885
US-20150004117-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR SUCLG1, DPM1, NACA FFAR3 4216/4885LCK 1382/4885FYN 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.