Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.57 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067789 | 0.88 | MAPT (0.62) | BCL6BCORMEN1KMT2AMAPT | |
| SCHEMBL6652907 | 0.82 | BCL6 (0.56) | BCL6BCORMEN1KMT2APOLB | |
| SCHEMBL11093863 | 0.81 | KDM4E (0.50) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL10617330 | 0.80 | BCL6 (0.63) | BCL6BCORMEN1KMT2AMAPT | |
| SCHEMBL6068061 | 0.78 | MAPT (0.58) | BCL6BCORMEN1KMT2AMAPT | |
| SCHEMBL6052442 | 0.78 | VCAM1 (0.53) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL29074795 | 0.78 | BCL6 (0.59) | BCL6BCORMEN1KMT2AMAPT | |
| SCHEMBL13384740 | 0.77 | L3MBTL1 (0.57) | BCL6BCORMEN1KMT2APOLB | |
| SCHEMBL15320008 | 0.77 | MAP2K1 (0.70) | PIN1 | |
| SCHEMBL16107845 | 0.75 | MYC (0.64) | BCL6BCORMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150005277-A1 | Protein Kinase Inhibitors and Uses Thereof | BEIGENE, LTD. (KY) | 2015-01-01 | — | — | US | disclosed |
| US-20150005277-A1 | Protein Kinase Inhibitors and Uses Thereof | BEIGENE, LTD. (KY) | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005277-A1 | Protein Kinase Inhibitors and Uses Thereof | BTK, ABL1, PRKACA | BCL6 197/4885BCOR 907/4885MEN1 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.