Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.56 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.56 |
| ▸ | CTSV | O60911 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067789 | 0.87 | MAPT (0.62) | BCL6BCORCTSVCTSLMAPT | |
| SCHEMBL16337674 | 0.82 | BCL6 (0.57) | BCL6BCORCTSVCTSLMAPT | |
| SCHEMBL5174834 | 0.81 | MAPT (0.75) | CTSVCTSLMAPTRECQLMEN1 | |
| SCHEMBL7875188 | 0.81 | CTSV (0.56) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL6652239 | 0.81 | CTSV (0.80) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL6657520 | 0.81 | CTSV (0.56) | BCL6BCORCTSVCTSLMAPT | |
| SCHEMBL3526801 | 0.80 | KMT2A (0.56) | MAPTRECQLMEN1KMT2AAKR1C3 | |
| SCHEMBL6655626 | 0.80 | MAPK13 (0.56) | MAPTRECQLMEN1KMT2APOLB | |
| SCHEMBL6657107 | 0.79 | HCAR3 (0.67) | CTSVCTSLMAPTMEN1KMT2A | |
| SCHEMBL10617330 | 0.79 | BCL6 (0.63) | BCL6BCORMAPTRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188388-C | Aminobenzophenones as inhibitors of interleukin and TNF | LEO PHARM PROD LTD (DK) | 2005-02-09 | — | — | CN | disclosed |
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |