Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960936 | 0.89 | KDM4E (0.64) | KDM4EMAPTCYP1A2PAX8MET | |
| Hydrochloric Acid SCHEMBL8126278 | 0.88 | KDM4E (0.62) | KDM4EMAPTCYP1A2PAX8MET | |
| SCHEMBL28492022 | 0.86 | KDM4E (0.47) | KDM4EMAPTCYP1A2PAX8MET | |
| SCHEMBL30006999 | 0.86 | KDM4E (0.47) | KDM4EMAPTCYP1A2PAX8MET | |
| SCHEMBL1551666 | 0.85 | KDM4E (0.46) | KDM4EMAPTCYP1A2PAX8MET | |
| SCHEMBL15109804 | 0.82 | KDM4E (0.44) | KDM4EMAPTCYP1A2PAX8MET | |
| SCHEMBL6491001 | 0.82 | PARP1 (0.52) | KDM4EMAPTCYP1A2METL3MBTL1 | |
| SCHEMBL8883407 | 0.82 | PAX8 (0.47) | KDM4EMAPTCYP1A2PAX8MET | |
| SCHEMBL10625865 | 0.81 | CYP11B1 (0.47) | KDM4ESMN1; SMN2CYP2C9CYP11B1CYP11B2 | |
| SCHEMBL15109765 | 0.81 | KDM4E (0.43) | KDM4EMAPTCYP1A2PAX8MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169951-A | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PYRIDINE (B) | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-02 | — | — | US | claimed |
| US-20030120088-A1 | Optically active azetidincarboxamide-coordinated transition metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-26 | — | — | US | disclosed |
| US-4169951-A | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PYRIDINE (B) | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120088-A1 | Optically active azetidincarboxamide-coordinated transition metal complexes | AAAS, AP1M1, AP2A1 | KDM4E 1847/4885MAPT 4413/4885CYP1A2 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.