Sugi Predict

Sugi Predict / Compounds / SCHEMBL1633998

SCHEMBL1633998

SCHEMBL1633998

O=C(O)Cc1ccc(/N=N/c2ccc(CC(=O)O)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 2/20 0.60
▸ CAMK2A Q9UQM7 1/20 0.60
▸ AKR1B1 P15121 1/20 0.58
▸ LMNA P02545 2/20 0.56
▸ GAA P10253 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ ABCC4 O15439 1/20 0.56
▸ PTGS1 P23219 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ ALDH1A1 P00352 4/20 0.53
▸ POLB P06746 3/20 0.53
▸ KDM4E B2RXH2 3/20 0.53
▸ MAPT P10636 3/20 0.53
▸ MEN1 O00255 3/20 0.53
▸ KMT2A Q03164 3/20 0.53
▸ CASP6 P55212 2/20 0.53
▸ CTDSP1 Q9GZU7 2/20 0.53
▸ NPC1 O15118 1/20 0.53
▸ IDO1 P14902 1/20 0.53
▸ MAPK1 P28482 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1633999 1.00 CA2 (0.60) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL3465398 0.94 AKR1B1 (0.64) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL3465399 0.94 AKR1B1 (0.64) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL7204862 0.90 MAPT (0.54) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL22637978 0.88 CA2 (0.48) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL22637979 0.88 CA2 (0.48) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL69614 0.84 CA2 (0.79) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL10076767 0.84 CA2 (0.58) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL13193599 0.82 CA2 (0.56) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL13712784 0.82 CA2 (0.56) CA2CAMK2AAKR1B1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220265684-A1 COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS HIGH TRAIL SPECIAL SITUATIONS LLC 2022-08-25 — — US claimed
EP-1773767-B1 SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS BIOCON LTD (IN) 2016-03-09 — — EP claimed
US-8754197-B2 Synthesis of azo bonded immunoregulatory compounds BIOCON LIMITED (IN) 2014-06-17 — — US claimed
US-20130096286-A1 SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS BIOCON LIMITED (IN) 2013-04-18 — — US claimed
US-8314214-B2 Synthesis of azo bonded immunoregulatory compounds BIOCON LIMITED (IN) 2012-11-20 — — US claimed
US-20110201792-A1 SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS BIOCON LIMITED (IN) 2011-08-18 — — US claimed
US-7932366-B2 Synthesis of azo bonded immunoregulatory compounds BIOCON LIMITED (IN) 2011-04-26 — — US claimed
US-20080033153-A1 Synthesis of Azo Bonded Immunoregulatory Compounds NOBEX CORPORATION 2008-02-07 — — US claimed
EP-1773767-A2 SYNTHEIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS Nobex Corporation (US) 2007-04-18 — — EP claimed
WO-2006014549-A2 SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS NOBEX CORPORATION (US) 2006-02-09 — — WO claimed
US-6583128-B2 Phenylazophenylacetic acid derivatives; treating inflammatory bowel disease NOBEX CORPORATION 2003-06-24 — — US claimed
EP-1313697-A2 IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE Nobex Corporation (US) 2003-05-28 — — EP claimed
US-20020049186-A1 Immunoregulatory compounds and derivatives and methods of treating diseases therewith NOBEX CORPORATION 2002-04-25 — — US claimed
WO-2002018324-A2 IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE NOBEX CORPORATION (US) 2002-03-07 — — WO claimed
US-12414979-B2 Compositions and methods for treating Sjogren's syndrome INTERLUDE BIOPHARMA CO. (US) 2025-09-16 — — US disclosed
WO-2022182703-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE 9 METERS BIOPHARMA, INC. (US) 2022-09-01 — — WO disclosed
US-20220265684-A1 COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS HIGH TRAIL SPECIAL SITUATIONS LLC 2022-08-25 — — US disclosed
US-6583128-B2 Phenylazophenylacetic acid derivatives; treating inflammatory bowel disease NOBEX CORPORATION 2003-06-24 — — US disclosed
US-20020049186-A1 Immunoregulatory compounds and derivatives and methods of treating diseases therewith NOBEX CORPORATION 2002-04-25 — — US disclosed
US-4141911-A REACTING DICARBOXYLIC ACID WITH MONOBASIC CHROMIC SALT, SURFACTANTS TOKYO SHIBAURA ELECTRIC CO., LTD. (JP) 1979-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096286-A1 SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS C3AR1, HRH4, FCGRT CA2 871/4885CAMK2A 4655/4885AKR1B1 53/4885
US-20110201792-A1 SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS CBR1, CBR3, HRH4 CA2 767/4885CAMK2A 4508/4885AKR1B1 18/4885
US-20080033153-A1 Synthesis of Azo Bonded Immunoregulatory Compounds HRH4, CBR1, ARG1 CA2 851/4885CAMK2A 4544/4885AKR1B1 26/4885
US-12414979-B2 Compositions and methods for treating Sjogren's syndrome SSB, PDE12, PDE3A CA2 471/4885CAMK2A 2774/4885AKR1B1 854/4885
US-20220265684-A1 COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS ALPI, SI, VIP CA2 58/4885CAMK2A 1667/4885AKR1B1 53/4885
US-20020049186-A1 Immunoregulatory compounds and derivatives and methods of treating diseases therewith MALT1, CCR1, HRH2 CA2 1538/4885CAMK2A 3762/4885AKR1B1 263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.