Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | KDM5C | P41229 | 3/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.32 |
| ▸ | KDM6B | O15054 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377561 | 1.00 | LMNA (0.43) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| SCHEMBL40381 | 0.82 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| SCHEMBL28981504 | 0.82 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Phosphine SCHEMBL1906956 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Water SCHEMBL4632803 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Hydrochloric Acid SCHEMBL61373 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| SCHEMBL2121788 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| SCHEMBL20872325 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Hydrochloric Acid SCHEMBL253519 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Hydrochloric Acid SCHEMBL38657781 | 0.79 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146920-A1 | DRUG CONJUGATES FOR THE TREATMENT OF OCULAR DISORDERS | ASCENDIS PHARMA OPHTHALMOLOGY DIVISION A/S (DK) | 2024-07-11 | — | — | WO | disclosed |
| EP-3299463-B1 | ENZYMATIC ENCODING | NUEVOLUTION AS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-3299463-A2 | ENZYMATIC ENCODING | Nuevolution A/S (DK) | 2018-03-28 | — | — | EP | disclosed |
| EP-2348125-B1 | Method for the synthesis of a bifunctional complex | NUEVOLUTION AS (DK) | 2017-06-21 | — | — | EP | disclosed |
| US-8466107-B2 | Fibrin-binding peptides and conjugates thereof | BRACCO IMAGING SPA (IT) | 2013-06-18 | — | — | US | disclosed |
| US-20120328512-A1 | Fibrin-Binding Peptides and Conjugates Thereof | BRACCO IMAGING S.P.A. (IT) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328512-A1 | Fibrin-Binding Peptides and Conjugates Thereof | FGB, F13B, F13A1 | LMNA 2412/4885EGLN1 1752/4885ALKBH5 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.