Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 known ✓ | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 known ✓ | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 2/20 | 0.40 |
| ▸ | GABRP known ✓ | O00591 | 1/20 | 0.36 |
| ▸ | GABRD known ✓ | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.36 |
| ▸ | SLC6A1 known ✓ | P30531 | 1/20 | 0.36 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.36 |
| ▸ | HDAC4 known ✓ | P56524 | 1/20 | 0.36 |
| ▸ | GABRE known ✓ | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL253519 | 1.00 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hydrochloric Acid SCHEMBL38657781 | 1.00 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hydrochloric Acid SCHEMBL559051 | 0.97 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL28981504 | 0.97 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL40381 | 0.97 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL2121788 | 0.93 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Phosphine SCHEMBL1906956 | 0.93 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| SCHEMBL20872325 | 0.93 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Water SCHEMBL4632803 | 0.93 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Hypochlorous Acid SCHEMBL3408792 | 0.90 | LMNA (0.47) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 34526 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146088-A1 | ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | GENENTECH, INC. (US) | 2026-05-28 | — | — | US | claimed |
| US-20260146955-A1 | SERS BIOSENSOR BASED ON CRISPR/CAS13A SYSTEM AND APPLICATION THEREOF | NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS (CN) | 2026-05-28 | — | — | US | claimed |
| EP-4748861-A1 | BISPECIFIC ANTIBODY, DRUG CONJUGATE THEREOF, AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2026-05-27 | — | — | EP | claimed |
| CN-117147651-B | G4-DNA tetrahedral probe electrode, preparation method, application and application method thereof | ZHEJIANG ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122084902-A | Method for enriching protein palmitoyl transferase substrate | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080121-A | Linker and use thereof in ligand drug conjugates | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076392-A | Preparation method of sulfhydryl functionalized and high-performance chitosan homogeneous membrane as film diffusion gradient technology binding phase | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080553-A | High-temperature-resistant sealing rubber material and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| WO-2026105108-A2 | AN ERGOTHIONEINE-CURCUMIN SYNERGISTIC ANTI-INFLAMMATORY AND ANTI-AGING COMPLEX COMPOSITION AND A PREPARATION METHOD THEREOF | ZIRAOUI ANAS (EG) | 2026-05-21 | — | — | WO | claimed |
| EP-4743521-A1 | FAST-CURED INTUMESCENT COATINGS | PPG Industries Ohio, Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| US-20040156880-A1 | Reversible hydrogel systems and methods therefor | DEPARTMENT OF VETERANS AFFAIRS, THE | 2004-08-12 | — | — | US | claimed |
| US-20040101920-A1 | Modification assisted profiling (MAP) methodology | REGENERON PHARMACEUTICALS, INC. | 2004-05-27 | — | — | US | claimed |
| WO-2004031213-A1 | METHOD FOR THE PREPARATION OF GROWTH HORMONE AND ANTAGONIST THEREOF HAVING LOWER LEVELS OF ISOFORM IMPURITIES THEREOF | PHARMACIA CORPORATION (US) | 2004-04-15 | — | — | WO | claimed |
| US-20040048315-A1 | Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof | PHARMACIA CORPORATION (US) | 2004-03-11 | — | — | US | claimed |
| US-20040038934-A1 | Thiol-modified hyaluronan | ANIKA THERAPEUTICS, INC. | 2004-02-26 | — | — | US | claimed |
| EP-1368309-A2 | THIOL-MODIFIED HYALURONAN | Anika Therapeutics Inc. (US) | 2003-12-10 | — | — | EP | claimed |
| US-6638711-B1 | Adding to amyloid; Alzheimer*s disease prevention and treatment | THE GENERAL HOSPITAL CORPORATION | 2003-10-28 | — | — | US | claimed |
| US-20020128512-A1 | Thiol- modified hyaluronan | ANIKA THERAPEUTICS, INC. | 2002-09-12 | — | — | US | claimed |
| WO-2002068383-A2 | THIOL-MODIFIED HYALURONAN | ANIKA THERAPEUTICS, INC. (US) | 2002-09-06 | — | — | WO | claimed |
| WO-2001022995-A1 | A METHOD FOR PREPARING CONJUGATES BETWEEN AN ANTIGEN AND MUCOSAL BINDING COMPONENT | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | claimed |