SCHEMBL16340703

SCHEMBL16340703

C#CC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC#C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NMT2 O60551 1/20 0.37
▸ NMT1 P30419 1/20 0.37
▸ NOD1 Q9Y239 1/20 0.37
▸ FURIN P09958 4/20 0.36
▸ FOLH1 Q04609 1/20 0.36
▸ CPA1 P15085 1/20 0.36
▸ CPA2 P48052 1/20 0.36
▸ CPA4 Q9UI42 1/20 0.36
▸ CPB2 Q96IY4 2/20 0.35
▸ GHSR Q92847 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16340673 0.92 NMT2 (0.38) NMT2NMT1FURINCPB2
SCHEMBL14669796 0.92 NMT2 (0.38) NMT2NMT1FURINFOLH1CPA1
SCHEMBL20529374 0.90 NMT2 (0.43) NMT2NMT1NOD1FURINFOLH1
SCHEMBL14669794 0.88 NMT1 (0.44) NMT2NMT1FURIN
SCHEMBL29353557 0.88 NMT2 (0.44) NMT2NMT1NOD1FOLH1CPA1
SCHEMBL29802019 0.88 NMT2 (0.44) NMT2NMT1NOD1FOLH1CPA1
SCHEMBL16340670 0.87 FOLH1 (0.42) NMT2NMT1FURINFOLH1CPA1
SCHEMBL14669746 0.86 GNPAT (0.45) FURINFOLH1CPA1CPA2CPA4
SCHEMBL14669549 0.86 GNPAT (0.45) FURINFOLH1CPA1CPA2CPA4
SCHEMBL31343441 0.84 NMT2 (0.41) NMT2NMT1NOD1FURINFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130029920-A1 Metal Nanoparticles BRIMBLE MARGARET A (NZ) 2013-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130029920-A1 Metal Nanoparticles PSTPIP2, PCNP, ANPEP NMT2 613/4885NMT1 395/4885NOD1 3353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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