Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 8/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669549 | 1.00 | GNPAT (0.45) | GNPATSIRT6SIRT1CPA1CPA2 | |
| SCHEMBL16340670 | 0.92 | FOLH1 (0.42) | CPA1CPA2CPA4FURINFOLH1 | |
| SCHEMBL29398096 | 0.90 | GNPAT (0.53) | GNPATSIRT6SIRT1CPA1CPA2 | |
| SCHEMBL14669796 | 0.87 | NMT2 (0.38) | SIRT6SIRT1CPA1CPA2CPA4 | |
| SCHEMBL14669948 | 0.87 | FOLH1 (0.49) | GNPATFOLH1CPB2 | |
| SCHEMBL16340703 | 0.86 | NMT2 (0.37) | CPA1CPA2CPA4FURINFOLH1 | |
| SCHEMBL14669806 | 0.84 | SLC6A5 (0.56) | SIRT6SIRT1 | |
| SCHEMBL10609149 | 0.84 | SIRT6 (0.53) | GNPATSIRT6SIRT1CPA1CPA2 | |
| SCHEMBL30598012 | 0.84 | SIRT6 (0.53) | GNPATSIRT6SIRT1CPA1CPA2 | |
| SCHEMBL29394494 | 0.83 | GNPAT (0.60) | GNPATSIRT6SIRT1CPA1CPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029920-A1 | Metal Nanoparticles | BRIMBLE MARGARET A (NZ) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029920-A1 | Metal Nanoparticles | PSTPIP2, PCNP, ANPEP | GNPAT 1707/4885SIRT6 4589/4885SIRT1 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.