SCHEMBL16340670

SCHEMBL16340670

C#CC[C@H](NC(=O)[C@H](CCCCN)NC(=O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC#C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.42
▸ CPB2 Q96IY4 5/20 0.40
▸ NMT2 O60551 1/20 0.38
▸ NMT1 P30419 1/20 0.38
▸ SLC15A2 Q16348 1/20 0.38
▸ SLC6A5 Q9Y345 1/20 0.37
▸ ERAP2 Q6P179 1/20 0.37
▸ ERAP1 Q9NZ08 1/20 0.37
▸ LNPEP Q9UIQ6 1/20 0.37
▸ FURIN P09958 1/20 0.36
▸ CPA1 P15085 1/20 0.36
▸ CPA2 P48052 1/20 0.36
▸ CPA4 Q9UI42 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14669796 0.95 NMT2 (0.38) FOLH1CPB2NMT2NMT1FURIN
SCHEMBL14669549 0.92 GNPAT (0.45) FOLH1CPB2FURINCPA1CPA2
SCHEMBL14669746 0.92 GNPAT (0.45) FOLH1CPB2FURINCPA1CPA2
SCHEMBL14669948 0.88 FOLH1 (0.49) FOLH1CPB2NMT2NMT1SLC6A5
SCHEMBL16340703 0.87 NMT2 (0.37) FOLH1CPB2NMT2NMT1FURIN
SCHEMBL14669806 0.85 SLC6A5 (0.56) NMT2NMT1SLC6A5
SCHEMBL16340673 0.83 NMT2 (0.38) CPB2NMT2NMT1FURIN
SCHEMBL9716627 0.82 FOLH1 (0.58) FOLH1CPB2NMT2NMT1SLC15A2
SCHEMBL9716630 0.82 FOLH1 (0.58) FOLH1CPB2NMT2NMT1SLC15A2
SCHEMBL29398096 0.81 GNPAT (0.53) FOLH1CPB2FURINCPA1CPA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130029920-A1 Metal Nanoparticles BRIMBLE MARGARET A (NZ) 2013-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130029920-A1 Metal Nanoparticles PSTPIP2, PCNP, ANPEP FOLH1 352/4885CPB2 230/4885NMT2 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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