Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353684 | 0.87 | NOS1 (0.39) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL28113585 | 0.81 | NOS1 (0.36) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL5409743 | 0.81 | NOS1 (0.36) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL221769 | 0.81 | ALDH1A1 (0.39) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL5209072 | 0.81 | ALDH1A1 (0.39) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL523836 | 0.79 | DGAT1 (0.41) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL27549577 | 0.79 | NOS1 (0.35) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL7936428 | 0.77 | NOS1 (0.34) | NOS1NOS3NOS2LMNAKMT2A | |
| SCHEMBL27572159 | 0.77 | NOS1 (0.37) | NOS1NOS3NOS2CA12CA14 | |
| SCHEMBL29019393 | 0.77 | NOS1 (0.39) | NOS1NOS3NOS2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951377-B2 | Methods, kits and compositions pertaining to the suppression of the detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid | APPLIED BIOSYSTEMS, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| CN-104370851-A | Synthesis method of 2-aminomethyl-thiazole hydrochloride | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2015-02-25 | — | — | CN | disclosed |
| US-20140378326-A1 | Methods, Kits and Compositions Pertaining to the Suppression of the Detectable Probe Binding to Randomly Distributed Repeat Sequences Genomic Nucleic Acid | DAKO DENMARK APS (DK) | 2014-12-25 | — | — | US | disclosed |