SCHEMBL16340993

SCHEMBL16340993

O=[N+]([O-])c1ccccc1-c1cccc2c1ccn2-c1cc(-c2ccccc2)cc(-c2ccccc2)n1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ EIF4E P06730 15/20 0.41
▸ LMNA P02545 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ CRHBP P24387 1/20 0.36
▸ CRHR2 Q13324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15802146 0.85 EIF4E (0.40) EIF4ELMNAMAPTHTTNPSR1
SCHEMBL16340803 0.84 EIF4E (0.42) EIF4ELMNAMAPTHTTNPSR1
SCHEMBL16321708 0.79 L3MBTL1 (0.44) LMNAMAPTHTTALDH1A1TDP1
SCHEMBL15568528 0.76 TDP1 (0.46) MAPTALDH1A1TDP1
SCHEMBL15114144 0.71 ALDH1A1 (0.47) LMNAMAPTHTTNPSR1ALDH1A1
SCHEMBL16750864 0.70 EIF4E (0.38) EIF4ELMNAMAPTHTTNPSR1
SCHEMBL16050110 0.70 HSP90AA1 (0.41) LMNAALDH1A1TDP1
SCHEMBL20426182 0.69 L3MBTL1 (0.39) MAPTHTTALDH1A1
SCHEMBL15596625 0.68 ALDH1A1 (0.47) EIF4ELMNAMAPTNPSR1ALDH1A1
SCHEMBL20426874 0.68 MEN1 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 — — US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 — — US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 — — US disclosed
US-20140374724-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2014-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same IDO1, IDO2, KYNU EIF4E 2674/4885LMNA 2814/4885MAPT 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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