Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 4/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111995 | 0.89 | CNR2 (0.34) | KCNH2CREBBPEP300CCNA2CDK2 | |
| SCHEMBL3411723 | 0.82 | MEN1 (0.39) | CREBBPEP300CCNA2CDK2CCNA1 | |
| SCHEMBL962706 | 0.80 | OPRM1 (0.35) | KCNH2CREBBPEP300KDM4CGCK | |
| SCHEMBL113428 | 0.80 | KCNH2 (0.36) | KCNH2CREBBPEP300NPY1RKDM4C | |
| SCHEMBL113716 | 0.80 | KCNH2 (0.41) | KCNH2CREBBPEP300MEN1KMT2A | |
| SCHEMBL113359 | 0.77 | ALOX5AP (0.34) | KCNH2CREBBPEP300GCKCNR2 | |
| SCHEMBL7014486 | 0.77 | KCNH2 (0.39) | KCNH2CREBBPEP300NPY1RKDM4C | |
| SCHEMBL7016133 | 0.75 | CFTR (0.40) | MEN1KMT2AKDM4C | |
| SCHEMBL962329 | 0.74 | HTR2C (0.33) | — | |
| SCHEMBL3412288 | 0.74 | KDM4C (0.44) | CREBBPEP300MEN1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424860-A1 | HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE | MSD K.K. (JP) | 2012-03-07 | — | — | EP | disclosed |