Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959896 | 0.88 | ALOX5AP (0.36) | MEN1KMT2AKDM4CCYP4F2CYP4A11 | |
| SCHEMBL113716 | 0.80 | KCNH2 (0.41) | MEN1KMT2APIK3CA | |
| SCHEMBL7014486 | 0.77 | KCNH2 (0.39) | KDM4C | |
| SCHEMBL3414164 | 0.77 | KDM4C (0.36) | MEN1KMT2ALNPEPKDM4C | |
| SCHEMBL113587 | 0.77 | ALOX5AP (0.36) | MEN1KMT2A | |
| SCHEMBL960988 | 0.76 | HTR2C (0.34) | PIK3C2BPIK3CAPIK3CGLNPEPATR | |
| SCHEMBL163419 | 0.75 | KCNH2 (0.37) | MEN1KMT2AKDM4C | |
| SCHEMBL112675 | 0.74 | KDM4C (0.46) | MEN1KMT2AKDM4CCYP4F2CYP4A11 | |
| SCHEMBL113428 | 0.74 | KCNH2 (0.36) | KDM4CATR | |
| SCHEMBL16950261 | 0.74 | KMO (0.55) | CFTRMEN1KMT2AKMOPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |