Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 10/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113716 | 0.88 | KCNH2 (0.41) | KCNH2MAPTNPY1RALDH1A1EP300 | |
| SCHEMBL113428 | 0.82 | KCNH2 (0.36) | KCNH2NPY1RGCKEP300CREBBP | |
| SCHEMBL962706 | 0.81 | OPRM1 (0.35) | KCNH2GCKEP300CREBBPKDM4C | |
| SCHEMBL111995 | 0.79 | CNR2 (0.34) | KCNH2NPC1RAB9ANPY1RGCK | |
| SCHEMBL7012955 | 0.78 | KCNH2 (0.35) | KCNH2NPY1REP300CREBBP | |
| SCHEMBL113359 | 0.78 | ALOX5AP (0.34) | KCNH2GCKEP300CREBBP | |
| SCHEMBL7016133 | 0.77 | CFTR (0.40) | KDM4C | |
| SCHEMBL163419 | 0.77 | KCNH2 (0.37) | KCNH2NPY1RGCKEP300CREBBP | |
| SCHEMBL7020498 | 0.76 | KCNH2 (0.41) | KCNH2SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL114808 | 0.72 | CREBBP (0.36) | SMN1; SMN2NPC1RAB9AGCKEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |