SCHEMBL1634390

SCHEMBL1634390

Cc1cccc(C)c1-c1cccc(COc2ccc(CCC(=O)O)c(F)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 1.00
FFAR4 Q5NUL3 2/20 1.00
DRD4 P21917 1/20 0.70
ADRA1D P25100 1/20 0.70
DRD3 P35462 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5115953 0.94 FFAR1 (0.88) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL5104972 0.94 FFAR1 (0.88) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL5107766 0.93 FFAR1 (0.86) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL1745115 0.91 FFAR1 (1.00) FFAR1FFAR4
SCHEMBL5105239 0.91 FFAR1 (0.83) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL1745231 0.90 FFAR1 (0.85) FFAR1FFAR4
SCHEMBL1744718 0.90 FFAR1 (0.82) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL1746843 0.89 FFAR1 (0.80) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL5114777 0.89 FFAR1 (0.80) FFAR1FFAR4DRD4ADRA1DDRD3
SCHEMBL1745038 0.89 FFAR1 (0.79) FFAR1FFAR4DRD4ADRA1DDRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-7932289-B2 Remedy for diabetes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-04-26 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
US-20080319077-A1 Remedy for Diabetes TAKEDA PHARMACEUTICAL COMPANY LIMITED 2008-12-25 US disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319077-A1 Remedy for Diabetes GPR119, GLP1R, GPR65 FFAR1 19/4885FFAR4 22/4885DRD4 2486/4885
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR FFAR1 33/4885FFAR4 44/4885DRD4 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.