Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627814 | 1.00 | APP (0.53) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL4981575 | 1.00 | APP (0.53) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL768675 | 1.00 | APP (0.53) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL348921 | 0.87 | ALDH1A1 (0.60) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL8809033 | 0.87 | ALDH1A1 (0.42) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL24303208 | 0.85 | APP (0.67) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3085759 | 0.85 | APP (0.67) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7651553 | 0.84 | APP (0.53) | APPMAPK1KDM4ETDP1 | |
| SCHEMBL466232 | 0.83 | APP (0.65) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10785918 | 0.82 | KCNA3 (0.43) | MAPK1ALDH1A1RECQLKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698943-A | Liquid crystal gel with light-emitting and light-responding characteristics, preparation method and application | 华中科技大学 | 2021-11-26 | — | — | CN | claimed |
| CN-113698943-A | Liquid crystal gel with light-emitting and light-responding characteristics, preparation method and application | 华中科技大学 | 2021-11-26 | — | — | CN | disclosed |
| EP-3016947-A1 | BENZOTHIOPHENE DERIVATIVES AS ESTROGEN RECEPTOR INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015000867-A1 | BENZOTHIOPHENE DERIVATIVES AS ESTROGEN RECEPTOR INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-01-08 | — | — | WO | disclosed |