Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16346124 | 1.00 | APP (0.53) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL17627814 | 1.00 | APP (0.53) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL768675 | 1.00 | APP (0.53) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL348921 | 0.87 | ALDH1A1 (0.60) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL8809033 | 0.87 | ALDH1A1 (0.42) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL24303208 | 0.85 | APP (0.67) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3085759 | 0.85 | APP (0.67) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7651553 | 0.84 | APP (0.53) | APPMAPK1KDM4ETDP1 | |
| SCHEMBL466232 | 0.83 | APP (0.65) | APPMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10785918 | 0.82 | KCNA3 (0.43) | MAPK1ALDH1A1RECQLKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | claimed |
| US-20200405696-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-31 | — | — | US | claimed |
| EP-3740493-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | Idorsia Pharmaceuticals Ltd (CH) | 2020-11-25 | — | — | EP | claimed |
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | disclosed |
| US-20200405696-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-31 | — | — | US | disclosed |
| EP-3740493-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | Idorsia Pharmaceuticals Ltd (CH) | 2020-11-25 | — | — | EP | disclosed |
| CN-110177677-A | three-dimensional printing | 惠普发展公司，有限责任合伙企业 | 2019-08-27 | — | — | CN | disclosed |
| CN-110036102-A | The method of cleaning compositions and cleaning equipment | 凯米罗总公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-108913054-A | A kind of dedicated optics rupture pressure disc of high viscosity Curved screen | 苏州袭麟光电科技产业有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-108893072-A | A kind of antistatic super abrasive optical protection layer | 苏州袭麟光电科技产业有限公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-104884601-B | Dress material liquid cleanser composition | 花王株式会社 | 2018-02-13 | — | — | CN | disclosed |
| US-20070048467-A1 | Information recording medium | HITACHI MAXELL, LTD. | 2007-03-01 | — | — | US | disclosed |
| EP-1249488-A1 | Softener composition | Kao Corporation (JP) | 2002-10-16 | — | — | EP | disclosed |
| US-6023130-A | Plasma display substrate and a production method thereof | KYOCERA CORPORATION (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0476456-B1 | Substituted 2-thiazolyl tetrazolium salt indicators | BAYER AG (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0476457-B1 | 2-Benzothiazolyl tetrazolium salt indicators | BAYER AG (US) | 1996-12-04 | — | — | EP | disclosed |
| EP-0476454-B1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | BAYER AG (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5322680-A | Chromogenic detector for medical diagnosis by forming formazan dyes chemical reduction | MILES INC. (US) | 1994-06-21 | — | — | US | disclosed |
| US-5300637-A | Useful in determination of reducing substances | MILES INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5126275-A | Chromogenic reducing indicators for reducing substances such as NADH | MILES INC. (US) | 1992-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405696-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDO2, TDO2, IDO1 | APP 4445/4885MAPK1 3817/4885ALDH1A1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.