SCHEMBL768675

SCHEMBL768675

OCCOCCOc1cc[c]cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 0.53
MAPK1 P28482 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
CYP3A4 P08684 1/20 0.49
CASP1 P29466 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SLCO1B3 Q9NPD5 1/20 0.49
SLCO1B1 Q9Y6L6 1/20 0.49
RECQL P46063 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 1/20 0.40
NR1I2 O75469 1/20 0.39
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16346124 1.00 APP (0.53) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL17627814 1.00 APP (0.53) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL4981575 1.00 APP (0.53) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL348921 0.87 ALDH1A1 (0.60) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL8809033 0.87 ALDH1A1 (0.42) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL24303208 0.85 APP (0.67) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL3085759 0.85 APP (0.67) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL7651553 0.84 APP (0.53) APPMAPK1KDM4ETDP1
SCHEMBL466232 0.83 APP (0.65) APPMAPK1ALDH1A1MEN1KMT2A
SCHEMBL10785918 0.82 KCNA3 (0.43) MAPK1ALDH1A1RECQLKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3740493-B1 INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE IDORSIA PHARMACEUTICALS LTD (CH) 2021-12-01 EP claimed
CN-214795270-U Multilayer co-extrusion composite light diffusion plate 杭州赛宁板材有限公司 2021-11-19 CN claimed
US-20200405696-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE IDORSIA PHARMACEUTICALS LTD (CH) 2020-12-31 US claimed
EP-3740493-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE Idorsia Pharmaceuticals Ltd (CH) 2020-11-25 EP claimed
CN-104877737-B Aerospace equipment special material emulsion cutting fluid and preparation method and purposes 上海德润宝特种润滑剂有限公司 2019-05-28 CN claimed
CN-107338088-A A kind of resistant to elevated temperatures lubricating oil and preparation method thereof 合肥择浚电气设备有限公司 2017-11-10 CN claimed
WO-2023180931-A1 COPOLYMERS AND METHODS OF MAKING AND USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-09-28 WO disclosed
WO-2023080235-A1 METHOD FOR MANUFACTURING PRINTED WIRING BOARD, METHOD FOR PEELING RESIST, AND RESIST PEELING PRETREATMENT LIQUID USED IN SAID METHODS 三菱瓦斯化学株式会社 2023-05-11 WO disclosed
CN-109535023-B DTPA (diethylenetriamine pentaacetic acid) neutral salt as well as preparation method and application thereof 天津天颐科苑科技有限公司 2022-04-15 CN disclosed
CN-114269891-A Hard surface cleaning compositions with reduced surface tension 埃科莱布美国股份有限公司 2022-04-01 CN disclosed
EP-3740493-B1 INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE IDORSIA PHARMACEUTICALS LTD (CH) 2021-12-01 EP disclosed
CN-112470079-A Cleaning method 花王株式会社 2021-03-09 CN disclosed
US-20200405696-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE IDORSIA PHARMACEUTICALS LTD (CH) 2020-12-31 US disclosed
US-7150955-B2 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-20050037281-A1 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
EP-0725051-B1 Copolyesters, molded articles from the same and aromatic triols used for producing the same KURARAY CO (JP) 1999-06-02 EP disclosed
US-5541052-A HAVING EMULSION LAYER CONTAINING NORMAL CRYSTAL SILVER HALIDE GRAINS WITH CONCAVE CRYSTAL FACE AND CORE/SHELL STRUCTURE WITH DIFFERENT COMPOSITION IN EACH KONICA CORPORATION (JP) 1996-07-30 US disclosed
EP-0410383-A1 Silver halide photographic material having improved keeping quality KONICA CORPORATION (JP) 1991-01-30 EP disclosed
US-4075830-A Solid adhesive compositions KONISHI CO., LTD. (JA) 1978-02-28 US disclosed
US-4056544-A Anthraquinone compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200405696-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE IDO2, TDO2, IDO1 APP 4445/4885MAPK1 3817/4885ALDH1A1 631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.