Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348327 | 0.95 | PPARA (0.46) | PPARAPPARGNPC1POLBRAB9A | |
| SCHEMBL16348306 | 0.95 | PPARG (0.51) | PPARAPPARGNPC1POLBRAB9A | |
| SCHEMBL16348312 | 0.92 | PPARA (0.43) | PPARAPPARGL3MBTL1NPC1POLB | |
| SCHEMBL16348362 | 0.91 | PPARG (0.42) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348369 | 0.90 | PPARA (0.48) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348314 | 0.90 | PPARA (0.52) | PPARAPPARGALDH1A1NPC1RAB9A | |
| SCHEMBL16348352 | 0.89 | PPARG (0.48) | PPARAPPARG | |
| SCHEMBL16348424 | 0.88 | PPARA (0.40) | PPARAPPARGALDH1A1PTGDR2KEAP1 | |
| SCHEMBL16350102 | 0.88 | PPARG (0.46) | PPARAPPARGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16348423 | 0.88 | PPARG (0.46) | PPARAPPARGNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |