Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.51 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348309 | 0.95 | PPARA (0.52) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348423 | 0.93 | PPARG (0.46) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16350102 | 0.93 | PPARG (0.46) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348327 | 0.92 | PPARA (0.46) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348357 | 0.90 | PPARG (0.47) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348360 | 0.90 | JMJD6 (0.42) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348312 | 0.89 | PPARA (0.43) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348334 | 0.87 | PPARG (0.55) | PPARGPPARATSPONPC1RAB9A | |
| SCHEMBL16348362 | 0.86 | PPARG (0.42) | PPARGPPARACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16348352 | 0.86 | PPARG (0.48) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |