Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348313 | 0.92 | PPARG (0.44) | PPARGPPARASLC6A4SLC22A12HTR2C | |
| SCHEMBL16348326 | 0.91 | PPARG (0.41) | PPARGSLC6A4HTTSLC22A12HTR2C | |
| SCHEMBL16348427 | 0.90 | PPARG (0.39) | PPARGPPARASLC6A4HTTHTR2C | |
| SCHEMBL16348327 | 0.90 | PPARA (0.46) | PPARGPPARA | |
| SCHEMBL16348309 | 0.89 | PPARA (0.52) | PPARGPPARA | |
| SCHEMBL16348312 | 0.87 | PPARA (0.43) | PPARGPPARA | |
| SCHEMBL16348306 | 0.86 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL16348368 | 0.84 | PPARG (0.38) | PPARGSLC6A4SLC22A12HTR2CHTR2B | |
| SCHEMBL16348351 | 0.83 | PPARG (0.47) | PPARGPPARASLC6A4HTTSLC22A12 | |
| SCHEMBL16348363 | 0.82 | PPARG (0.52) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |