Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348340 | 0.91 | PTGER1 (0.41) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348309 | 0.91 | PPARA (0.52) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348339 | 0.91 | PPARG (0.39) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348310 | 0.89 | PPARG (0.41) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348364 | 0.88 | PPARG (0.45) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348342 | 0.86 | NPC1 (0.41) | PPARGPPARAALDH1A1NPSR1MAPT | |
| SCHEMBL16348327 | 0.86 | PPARA (0.46) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL16348360 | 0.86 | JMJD6 (0.42) | PPARGPPARAALDH1A1LMNAMAPT | |
| SCHEMBL16348306 | 0.86 | PPARG (0.51) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL16348367 | 0.84 | JMJD6 (0.39) | ALDH1A1MAPTNPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |