Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348334 | 0.94 | PPARG (0.55) | PPARGPPARAKEAP1NFE2L2SCN9A | |
| SCHEMBL16348364 | 0.90 | PPARG (0.45) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348309 | 0.87 | PPARA (0.52) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348369 | 0.86 | PPARA (0.48) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348314 | 0.85 | PPARA (0.52) | PPARGPPARAALDH1A1KDM4EKEAP1 | |
| SCHEMBL16348333 | 0.84 | PPARG (0.51) | PPARGPPARAKDM4EPTGDR2MEN1 | |
| SCHEMBL16348363 | 0.82 | PPARG (0.52) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348327 | 0.82 | PPARA (0.46) | PPARGPPARAPTGDR2POLBKMT2A | |
| SCHEMBL16348365 | 0.81 | PPARG (0.40) | PPARGPPARAALDH1A1NPSR1KDM4E | |
| SCHEMBL16348306 | 0.81 | PPARG (0.51) | PPARGPPARAPOLBKMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |