Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348337 | 0.94 | PPARG (0.56) | PPARGPPARASCN9AKEAP1NFE2L2 | |
| SCHEMBL16348365 | 0.87 | PPARG (0.40) | PPARGPPARANPC1RAB9ASCN9A | |
| SCHEMBL16348306 | 0.87 | PPARG (0.51) | PPARGPPARANPC1RAB9ATSHR | |
| SCHEMBL16348357 | 0.85 | PPARG (0.47) | PPARGPPARATSHRKEAP1NFE2L2 | |
| SCHEMBL16348364 | 0.84 | PPARG (0.45) | PPARGPPARASCN9AMAPT | |
| SCHEMBL16348333 | 0.84 | PPARG (0.51) | PPARGPPARAKEAP1NFE2L2MAPT | |
| SCHEMBL16348309 | 0.81 | PPARA (0.52) | PPARGPPARANPC1RAB9AKEAP1 | |
| SCHEMBL16348369 | 0.80 | PPARA (0.48) | PPARGPPARAKEAP1NFE2L2TSPO | |
| SCHEMBL16348423 | 0.80 | PPARG (0.46) | PPARGPPARANPC1RAB9ATSHR | |
| SCHEMBL16350102 | 0.80 | PPARG (0.46) | PPARGPPARANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |