Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348427 | 0.91 | PPARG (0.39) | PTGER1SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL16348326 | 0.90 | PPARG (0.41) | JMJD6SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL16348368 | 0.83 | PPARG (0.38) | SLC6A4HTR2CHTR2BHTR6MAPT | |
| SCHEMBL16348367 | 0.83 | JMJD6 (0.39) | JMJD6MAPTADORA1SMN1; SMN2ELANE | |
| SCHEMBL16348380 | 0.83 | JMJD6 (0.40) | JMJD6PTGER1MAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL16348352 | 0.81 | PPARG (0.48) | SLC6A4HTR2CHTR2BHTR6PPARG | |
| SCHEMBL16348342 | 0.80 | NPC1 (0.41) | JMJD6MAPTADORA1SMN1; SMN2ELANE | |
| SCHEMBL16348424 | 0.79 | PPARA (0.40) | JMJD6PTGER1PPARG | |
| SCHEMBL13523099 | 0.79 | PTGFR (0.41) | PTGER1SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL13523061 | 0.77 | PTGFR (0.41) | PTGER1SLC6A4HTR2CHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |