Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348342 | 0.93 | NPC1 (0.41) | JMJD6NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL16348312 | 0.91 | PPARA (0.43) | NPC1POLBRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL16348360 | 0.89 | JMJD6 (0.42) | JMJD6NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL16348380 | 0.89 | JMJD6 (0.40) | JMJD6NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16348326 | 0.88 | PPARG (0.41) | JMJD6SMN1; SMN2MAPT | |
| SCHEMBL16348362 | 0.84 | PPARG (0.42) | JMJD6NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL16348327 | 0.84 | PPARA (0.46) | JMJD6NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL16348341 | 0.83 | JMJD6 (0.39) | JMJD6SMN1; SMN2MAPTELANECYP2C9 | |
| SCHEMBL16348309 | 0.82 | PPARA (0.52) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16348368 | 0.81 | PPARG (0.38) | SMN1; SMN2MAPTELANEADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |