Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523181 | 0.82 | IDO1 (0.44) | HPGDKDM4ETSHRIDO1JMJD6 | |
| SCHEMBL8005007 | 0.74 | MAPT (0.41) | HPGDKDM4EJMJD6SMN1; SMN2NPC1 | |
| SCHEMBL29790468 | 0.71 | ADRA1A (0.47) | KDM4EIDO1JMJD6SMN1; SMN2NPC1 | |
| SCHEMBL16911568 | 0.71 | ACSS2 (0.47) | JMJD6SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL21051373 | 0.70 | ACSS2 (0.43) | GFERHPGDKDM4ETSHRJMJD6 | |
| SCHEMBL23923765 | 0.70 | JMJD6 (0.44) | KDM4EJMJD6SMN1; SMN2NPC1GAA | |
| SCHEMBL2050729 | 0.69 | JMJD6 (0.37) | HPGDKDM4EJMJD6SMN1; SMN2NPC1 | |
| SCHEMBL6448325 | 0.68 | MAPT (0.38) | GFERHPGDKDM4ETSHRAPOBEC3G | |
| SCHEMBL6449954 | 0.68 | GRM5 (0.46) | GFERHPGDKDM4ETSHRAPOBEC3G | |
| SCHEMBL8743338 | 0.68 | ALOX15 (0.62) | GFERHPGDKDM4ETSHRAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |