Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348331 | 0.86 | S1PR4 (0.39) | EPHX2DRD2DRD4DRD3IDO1 | |
| SCHEMBL16348400 | 0.84 | KDM4E (0.38) | EPHX2DRD2DRD4DRD3IDO1 | |
| SCHEMBL16348343 | 0.80 | PTPN11 (0.48) | EPHX2DRD2DRD4DRD3IDO1 | |
| SCHEMBL16348378 | 0.80 | P2RX7 (0.42) | EPHX2DRD2DRD4DRD3IDO1 | |
| SCHEMBL16348399 | 0.77 | PPARG (0.47) | PPARAFFAR1PPARGTSHR | |
| SCHEMBL16348437 | 0.76 | PPARA (0.47) | DRD2DRD4DRD3PPARAPPARG | |
| SCHEMBL5116066 | 0.75 | CA2 (0.44) | EPHX2DRD2DRD4DRD3FFAR1 | |
| SCHEMBL14098695 | 0.75 | MAPT (0.45) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16348440 | 0.75 | PPARA (0.41) | PPARAFFAR1PPARGCASP3SENP8 | |
| SCHEMBL16348379 | 0.74 | EPHX2 (0.44) | EPHX2IDO1KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |