Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348400 | 0.88 | KDM4E (0.38) | P2RX7KDM4ENPC1LMNACASP3 | |
| SCHEMBL16348331 | 0.83 | S1PR4 (0.39) | KDM4ENPC1LMNACASP3CDK9 | |
| SCHEMBL16348376 | 0.80 | EPHX2 (0.36) | KDM4ENPC1LMNACASP3CDK9 | |
| SCHEMBL16348398 | 0.77 | PPARA (0.43) | P2RX7KDM4ECASP3SENP7MEN1 | |
| SCHEMBL16348343 | 0.77 | PTPN11 (0.48) | KDM4ENPC1LMNACASP3CDK9 | |
| SCHEMBL16348442 | 0.77 | PPARA (0.44) | CASP3SENP7MEN1KMT2AFFAR1 | |
| SCHEMBL14098695 | 0.74 | MAPT (0.45) | KDM4ELMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5116066 | 0.73 | CA2 (0.44) | NPC1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16348379 | 0.71 | EPHX2 (0.44) | KDM4ENPC1LMNACASP3CDK9 | |
| SCHEMBL16348383 | 0.65 | DRD2 (0.56) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |