Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348405 | 0.94 | PPARG (0.53) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL16348384 | 0.88 | PPARG (0.48) | PPARAPPARGCTSAHTR2CHTR2B | |
| SCHEMBL16348403 | 0.83 | PPARA (0.54) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL13522844 | 0.83 | PPARG (0.57) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL13522838 | 0.80 | PPARG (0.54) | PPARAPPARGMEN1POLBCASP3 | |
| SCHEMBL13523076 | 0.79 | PPARG (0.50) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL13522846 | 0.78 | PPARG (0.51) | PPARAPPARGMEN1POLBCASP3 | |
| SCHEMBL16348372 | 0.78 | PPARG (0.56) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL16348354 | 0.78 | PPARG (0.56) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL13522845 | 0.77 | PTGS2 (0.48) | PPARAPPARGKDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |