Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523182 | 0.86 | IDO1 (0.49) | IDO1MAPTALDH1A1PIM1EPHX2 | |
| SCHEMBL364560 | 0.78 | MAPT (0.65) | IDO1MAPTALDH1A1PIM1EPHX2 | |
| SCHEMBL16348323 | 0.77 | EPHX2 (0.46) | IDO1MAPTALDH1A1PIM1EPHX2 | |
| SCHEMBL13212232 | 0.70 | SLC9A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL16348338 | 0.70 | IDO1 (0.42) | IDO1MAPTALDH1A1PIM1EPHX2 | |
| SCHEMBL28839402 | 0.69 | SLC9A1 (0.40) | ALDH1A1KMT2AMAPK1DGAT1ESR1 | |
| SCHEMBL16348324 | 0.69 | GFER (0.46) | IDO1MAPTKDM4ENPC1LMNA | |
| SCHEMBL6652319 | 0.69 | P2RX7 (0.38) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL6650791 | 0.68 | P2RX7 (0.40) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL13522938 | 0.68 | HSP90AA1 (0.51) | IDO1MAPTALDH1A1PIM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |