Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523181 | 0.86 | IDO1 (0.44) | IDO1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL366947 | 0.79 | IDO1 (0.50) | IDO1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11679229 | 0.77 | CYP19A1 (0.49) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL16348304 | 0.77 | CACNA1G (0.45) | IDO1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL16348322 | 0.77 | IDO1 (0.41) | IDO1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL16348357 | 0.74 | PPARG (0.47) | KDM4ELMNAHPGDALDH1A1MEN1 | |
| SCHEMBL16348426 | 0.72 | PSEN1 (0.38) | KDM4EMAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL16348339 | 0.71 | PPARG (0.39) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16348394 | 0.70 | IDO1 (0.48) | IDO1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL23402376 | 0.69 | ALDH1A1 (0.37) | KDM4ESMN1; SMN2LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |