Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721217 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13172419 | 0.76 | LMNA (0.50) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15442925 | 0.76 | POLB (0.49) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3579429 | 0.75 | LMNA (0.49) | ALDH1A1HPGDMAPK1TDP1LMNA | |
| SCHEMBL16348410 | 0.73 | PPARG (0.59) | ALDH1A1HPGDMAPK1TDP1LMNA | |
| SCHEMBL13172180 | 0.73 | POLB (0.47) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16348349 | 0.72 | PPARG (0.58) | ALDH1A1TSHRKDM4E | |
| SCHEMBL2202595 | 0.71 | LMNA (0.68) | ALDH1A1HPGDMAPK1TDP1LMNA | |
| SCHEMBL28103303 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13172131 | 0.70 | POLB (0.43) | ALDH1A1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |