SCHEMBL16348682

SCHEMBL16348682

Cn1c(=O)ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c1=O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.48
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ADRB1 P08588 1/20 0.48
DNMT1 P26358 1/20 0.48
TK2 O00142 1/20 0.47
ALOX12 P18054 1/20 0.46
ADRA1A P35348 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24420755 1.00 TK1 (0.48) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL27054419 1.00 TK1 (0.48) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL24420515 1.00 TK1 (0.48) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL27056572 0.91 DUT (0.42) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL20369020 0.87 TK1 (0.46) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL8840638 0.87 TK1 (0.46) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL29716313 0.87 TK1 (0.46) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL8840636 0.87 TK1 (0.46) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL26181033 0.87 TK1 (0.46) TK1LMNASMN1; SMN2ADRB1DNMT1
SCHEMBL2056583 0.85 TK1 (0.46) TK1LMNASMN1; SMN2ADRB1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
EP-4404942-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2024-07-31 EP disclosed
EP-4240849-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2023-09-13 EP disclosed
CN-116507724-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2023-07-28 CN disclosed
WO-2023049477-A2 COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-03-30 WO disclosed
US-20210254067-A1 MICRORNA INHIBITORS FOR USE IN TREATING METABOLIC DISEASES HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH) (DE) 2021-08-19 US disclosed
EP-3850099-A1 MICRORNA INHIBITORS FOR USE IN TREATING METABOLIC DISEASES Helmholtz Zentrum München Forschungszentrum für Gesundheit und Umwelt GmbH (DE) 2021-07-21 EP disclosed
EP-3775277-A1 METHOD FOR DIAGNOSING DISEASES USING MULTIPLEX FLUORESCENCE AND SEQUENCING MultiplexDX, s.r.o. (SK) 2021-02-17 EP disclosed
WO-2020070325-A1 METHOD FOR DIAGNOSING DISEASES USING MULTIPLEX FLUORESCENCE AND SEQUENCING MULTIPLEX DX (SK) 2020-04-09 WO disclosed
WO-2020053186-A1 MICRORNA INHIBITORS FOR USE IN TREATING METABOLIC DISEASES HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2020-03-19 WO disclosed
WO-2017097973-A1 MODIFIED NUCLEOSIDES UNIVERSITAET KONSTANZ (DE) 2017-06-15 WO disclosed
US-9605261-B2 RNA synthesis—phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end CHEMGENES CORPORATION (US) 2017-03-28 US disclosed
US-20150218557-A1 RNA SYNTHESIS-PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION, AND APPLICATION IN CONVENIENT INTRODUCTION OF LIGANDS, CHROMOPHORES AND MODIFICATIONS OF SYNTHETIC RNA AT THE 3'-END CHEMGENES CORPORATION 2015-08-06 US disclosed
US-8933214-B2 RNA synthesis—phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end CHEMGENES CORPORATION (US) 2015-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 TK1 950/4885LMNA 240/4885SMN1; SMN2 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.