Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377140 | 0.80 | ALDH1A1 (0.46) | GAAIDO1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16377150 | 0.79 | IDO1 (0.42) | IDO1ALDH1A1LMNAHTT | |
| SCHEMBL16377138 | 0.79 | TP53 (0.53) | GAAIDO1ALDH1A1LMNAMAPT | |
| SCHEMBL16377143 | 0.79 | IDO1 (0.62) | GAAIDO1KMT2AMEN1 | |
| SCHEMBL16377139 | 0.79 | ALDH1A1 (0.54) | IDO1ALDH1A1MAPT | |
| SCHEMBL16377152 | 0.79 | PGR (0.45) | IDO1ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL8056975 | 0.78 | GAA (0.61) | GAAIDO1TDO2ATMALDH1A1 | |
| SCHEMBL31453077 | 0.78 | GAA (0.61) | GAAIDO1TDO2ATMALDH1A1 | |
| SCHEMBL31453076 | 0.78 | GAA (0.61) | GAAIDO1TDO2ATMALDH1A1 | |
| SCHEMBL15229055 | 0.78 | GAA (0.61) | GAAIDO1TDO2ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | claimed |
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |