Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377140 | 0.84 | ALDH1A1 (0.46) | PGRCYP2C19CYP1A2MAPTIDO1 | |
| SCHEMBL16377139 | 0.83 | ALDH1A1 (0.54) | PGRCYP2C19MAPTIDO1AKR1B1 | |
| SCHEMBL16377138 | 0.83 | TP53 (0.53) | PGRCYP2C19MAPTKMT2AIDO1 | |
| SCHEMBL16381654 | 0.79 | CHRM5 (0.55) | PGRMAPTIDO1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16348696 | 0.79 | GAA (0.54) | MAPTKMT2AIDO1HTTSMN1; SMN2 | |
| SCHEMBL12440856 | 0.77 | IDO1 (0.54) | CYP2C19CYP1A2MAPTKMT2AIDO1 | |
| SCHEMBL700627 | 0.77 | IDO1 (0.69) | CYP2C19CYP1A2MAPTKMT2AIDO1 | |
| SCHEMBL699106 | 0.74 | IDO1 (0.48) | CYP2C19CYP1A2MAPTKMT2AIDO1 | |
| SCHEMBL25313851 | 0.73 | CYP1A2 (0.53) | PGRCYP2C19CYP1A2MAPTKMT2A | |
| SCHEMBL30132814 | 0.73 | CYP1A2 (0.53) | PGRCYP2C19CYP1A2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |
| US-8933248-B2 | 3-substituted-3-hydroxy oxindole derivatives and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-01-13 | — | — | US | disclosed |