Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16300658 | 1.00 | ATM (0.40) | ATMMMP2ANPEPNR1H2HRH3 | |
| SCHEMBL16316489 | 1.00 | ATM (0.40) | ATMMMP2ANPEPNR1H2HRH3 | |
| SCHEMBL14524823 | 0.80 | MMP2 (0.46) | ATMMMP2ANPEPHRH3 | |
| SCHEMBL14155394 | 0.77 | MMP2 (0.34) | ATMMMP2ANPEP | |
| SCHEMBL16316032 | 0.76 | ATM (0.43) | ATMMMP2ANPEPHRH3 | |
| SCHEMBL9603348 | 0.76 | ATM (0.40) | ATM | |
| SCHEMBL9603346 | 0.76 | ATM (0.40) | ATM | |
| SCHEMBL9603350 | 0.76 | ATM (0.40) | ATM | |
| SCHEMBL31573201 | 0.75 | UCHL1 (0.36) | NR1H2 | |
| SCHEMBL16300598 | 0.73 | ATM (0.43) | ATMMMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |